On Earth Day April 22, science-lovers will gather on the National Mall in Washington, D.C., and in dozens of satellite marches across the United States and even around the globe.
Celebrity headliners set to make an appearance during Saturday's "March for Science" event include TV personality Bill Nye, actress Mayim Bialik and more.
According to the Earth Day Network, the nonprofit in charge of programming for the day, activities include a speaker series at 10 a.m. ET, pop-up TED Talks and a march toward the Capitol.
Mayim Bialik said she'll be showing up to the march in a lab coat at the San Jose march.
Mark Ruffalo tweeted about his attendance to his 3.13 million Twitter followers.
Let the science sign creations begin.