WATCH | The Senate votes on Betsy DeVos' appointment as education secretary.
Hundreds of New York students walked out of class in response to DeVos' appointment.
UPDATE 12:30 p.m.
After the Senate vote on Betsy DeVos' nomination as education secretary tied 50-50, with two Republicans breaking an otherwise party-line vote, Vice President Pence broke the tie in Devos' favor. This marked the first time a Cabinet nominee ever required a vice-presidential tiebreaker.
Sens. Susan Collins (R-ME) and Lisa Murkowski (R-AL) were the only senators to vote against the party line.
Democratic Senators pulled an all-nighter trying to block the nomination of Betsy DeVos as education secretary. Senators traded speaking slots starting at noon Monday, aiming to continue until noon Tuesday, when DeVos' confirmation vote is scheduled.
Two Republican Senators have said they will vote against her. If one more Republican does so, DeVos' nomination will be sunk. As it stands, Vice President Pence will break the 50-50 tie in DeVos' favor.
Senate Dems protest to keep the failed status quo. Betsy DeVos is a reformer, and she is going to be a great Education Sec. for our kids!— President Trump (@POTUS) February 7, 2017
President Trump criticized the protesters for supporting the "failed status quo."
WATCH | Here's an excerpt of the 24-hour series of speech.
WATCH | Sen. Elizabeth Warren (D-MA) did not mince words against DeVos, saying it was "hard to imagine a worse choice" for the education secretary position.
WATCH | Sen. Kamala Harris (D-CA) said DeVos "has not done her homework."
WATCH | Sen. Al Franken (D-NY) attacked DeVos' lack of education experience, saying the job was "not for amateurs."
All of the drama may not end up advancing the Democrats' cause, however. So far, only Sens. Susan Collins (R-ME) and Lisa Murkowski (R-AL) have said they will vote against the party line. The third vote Democrats seek remains elusive.
And the Senate may be in for more long nights. Sen. John Cornyn (R-TX) said the Senate session would not end until DeVos and three other Cabinet nominees had been approved: Sen. Jeff Sessions (R-AL) for attorney general, Rep. Tom Price (R-GA) for health and human services secretary, and Steven Mnuchin as treasury secretary.
Former vice presidential hopeful Sen. Tim Kaine (D-VA) seemed fine with an early morning slot.
Some supporters joined the Senate's collective insomnia.