A flight set to leave from Chicago's O'Hare airport caught fire on the runway at around 2:30 p.m., reports NBC Chicago.
Emergency services responded at the scene of the fire and sent 20 people to the hospital for minor injuries. There were 161 passengers and nine crew members on the plane.
The visual of the plane on fire is frightening.
People evacuated out onto the runway as the plane went up in flames.
The Chicago Fire Department is trying to keep people updated via Twitter.
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