Nearly 200 nations agreed to limit the use of greenhouse gases to fight climate change.
The Kigali Agreement announced Saturday morning, caps and reduces the use of hydrofluorocarbons in a gradual process beginning in 2019 with action by developed countries including the United States, the world's second worst polluter.
More than 100 developing countries, including China, the world's top carbon emitter, will start taking action in 2024.
The "landmark" deal will reduce the use of hydrofluorocarbons (HFCs), the world's fastest growing greenhouse gases, the United Nations Environment Program said in a statement.
The deal could prevent up to 0.5 C of global warming by the end of this century.
President Obama called the deal an ambitious "solution to this looming crisis."
The U.N. says the next meeting in 2017 will determine how much of the billions of dollars needed to finance the reduction of HFCs will be provided by countries.
The Associated Press contributed to this report.