WATCH: With Tuesday's reports that Angelina Jolie has filed for divorce from Brad Pitt, Circa looks back on their high-profile relationship.
2004: Jolie and Pitt film "Mr. & Mrs. Smith," in which they play a married couple.
2005: Pitt and Jennifer Aniston divorce in March; they'd married five years earlier.
2005: "Mr. & Mrs. Smith" is released in June, and grosses $478 million worldwide.
2006: Pitt legally named father to Jolie's two adopted children, Maddox and Zahara, in January.
2006: Jolie and Pitt's first biological child, Shiloh, is born in May, in Namibia.
2007: Jolie and Pitt adopt son Pax from a Vietnamese orphanage.
2008: Jolie gives birth to twins, Knox and Vivienne, in France.
2014: Jolie marries Pitt in a private August ceremony in Chateau Miraval, France.
2014: Jolie directs herself and Pitt in "By the Sea" while they're on their honeymoon.
2015: "By the Sea" is released in November, but grosses just $538,000 worldwide.
2016: Jolie files for divorce, according to CNN.