Actress and transgender activist, Alexis Arquette, died Sunday following a lengthy illness. She was 47.
Arquette's brother, Richmond Arquette, confirmed her death on Facebook, according to Us Weekly.
"Our brother Robert, who became our brother Alexis, who became our sister Alexis, who became our brother Alexis, passed this morning September 11, at 12:32 a.m.," Richmond Arquette wrote.
"He was surrounded by all of his brothers and sisters, one of his nieces and several other loved ones. We were playing music for him and he passed during David Bowie's Starman. As per his wishes, we cheered at the moment that he transitioned to another dimension."
Born Robert, Alexis Arquette was best known for roles in "The Wedding Singer" and "Pulp Fiction."
R.I.P my sister Alexis Arquette. Another bright light gone out far too soon. Love to the family and all that loved Alexis.— Boy George (@BoyGeorge) September 11, 2016
Boy George, who inspired her role in "The Wedding Singer" posted a tribute on Twitter.
She was the sibling of actors Rosanna, David and Patricia Arquette.
In February, David Arquette reportedly said that Alexis no longer identified as transgender, according to CNN.
"She was like, 'Yeah, sometimes I'll be a man, sometimes I'll be a woman. I like to refer to myself as gender suspicious,'" David Arquette told Entertainment Tonight.
According to CNN, Arquette was one of the earliest high-profile advocates for transgender rights.
Arquette's cause of death was not specified.